In spring 2016, the UKQSAR group is going to join up with the PhysChem Forum to put on a joint meeting to be hosted by GSK. Day One of the meeting will be held at the Holiday Inn in Stevenage and will begin after lunch with an afternoon session. An evening session with a Plenary lecture and Symposium dinner will complete the day.
The second day will be held at the GSK Medicines Research site will follow a format more familiar to UKQSAR meeting attendees with a morning and afternoon session interspersed with coffee and lunch during which posters will be on display.
The date will be March 15th / 16th 2016 at GSK Stevenage Hertfordshire.
The Registration Form is now available for download and completion. Registration deadline extended to Monday 29th February 2016.
To register for the Symposium Dinner please see this Symposium Dinner registration Information. Pre Registration is neccessay.
Click for Additional Accomodation and Travel information
Tuesday March 15th 2016
| From | To | Location | Activity |
| 12:30 | 01:30 | Holiday Inn Stevenage | Registration |
| 01:30 | 01:40 | HIS | Welcome and house rules |
| 01:40 | 02:20 | HIS | Jan Kihlberg – Uppsala University
Charting the unknown – novel targets and oral bioavailability beyond the rule of 5 |
| 02:20 | 03:00 | HIS | Pat Barton Nottingham University
The interplay between OATP1B1, BSEP and MRP4 in Drug Induced Liver Injury (DILI) |
| 03:00 | 03:30 | HIS | Coffee & Networking |
| 03:30 | 04:10 | HIS | Rasmus Leth(TBC) – Optibrium
Which P450: Predicting Which Cytochrome P450 Isoforms are involved in the Metabolism of a Xenobiotic Please contact Rasmus Leth [rasmusleth87@gmail.com] for copy of the slides |
| 04:10 | 05:00 | HIS | Student Presentations:
Natalia Aniceto – Medway School of Pharmacy Max Robinson – University of Loughborough CAD quantification in Physical Chemistry |
| 05:00 | 05:05 | HIS | Wrap up |
| Session 2 | Chair: | ||
| 06:00 | 06:30 | Holiday Inn Stevenage | Drinks reception & late Registration |
| 06:30 | 07:30 | HIS | Plenary Lecture – Mike Hann GSK
Moving beyond Molecular Obesity and the other addictions in drug discovery |
| 08:00 | 10:00 | HIS | Symposium Dinner |
Wednesday March 16th 2016
| From | To | Location | Activity |
| GSK Stevenage | Arrive at GSK | ||
| 08:30 | 09:00 | PFA Ash &Elm | late registration & poster setup |
| 09:00 | 09:10 | GSK Lecture theatre | Robin Carr – GSK STV Site Head
Welcome |
| 09:10 | 09:50 | GSK Lecture theatre | Susanne Winniwater – AZ Molndal
In silico models to estimate a drugs brain penetration likeliness |
| 09:50 | 10:30 | GSK Lecture theatre | David Livermore – Takeda |
| 10:30 | 11:00 | PFA Ash &Elm | Coffee & Poster viewing |
| 11:00 | 11:40 | GSK Lecture theatre | Mike Hann
Measuring drug uptake in cells – from high throughput to imaging Mass Spectrometry |
| 11:40 | 12:00 | GSK Lecture theatre | Graeme Robb – AZ
DOE for SAR: Design of Experiments for Structure Activity Relationships |
| 12:00 | 12:20 | GSK Lecture theatre | Flash Poster session – click to see listing |
| 12:20 | 01:40 | PFA Ash &Elm | lunch & Poster viewing |
| Session 4 | Chair: | ||
| 01:40 | 02:20 | GSK Lecture theatre | David Palmer – Strathclyde Uni
PhysChem Property Prediction from Molecular Theories of Solvation |
| 02:20 | 03:00 | GSK Lecture theatre | Sarah Whalley from Syngenta
Are Agrochemical Compounds really any different to Pharmaceuticals? |
| 03:00 | 03:30 | PFA Ash &Elm | Best Poster Award, coffee & poster viewing |
| 03:30 | 04:10 | GSK Lecture theatre | Steve Charlton – Nottingham Uni
Stuck in the membrane with you: The influence of drug- phospholipid interactions on receptor pharmacology |
| 04:10 | 04:50 | GSK Lecture theatre | Dr Taravat Ghafourian -University of Sussex
Physicochemical factors controlling drug distribution in the body. Dr Andrius Sazonovas, ACD/Labs Smart Structure Design: employing physchem insights in virtual lead optimization. |
| 04:50 | 05:00 | GSK Lecture theatre | Wrap up and Depart |